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Itai-Itai disease(Cadmium poisoning)

Around Jinzu river in Toyama

Feeling pain on lower back and lower extremity.
Patient will have a terrible ache to walk.
When they have a cough and sneeze, they break their costae and have deformity of their body.
This disease harms the kidneys

Chronic poisoning by cadmium. People who living by Jinzu river eat crops made with cadmium-contaminated water.

Cadmium flowed from metalliferous mine by upper reach of Jinzu river to lower.

Ground onset of the disease